While human overdose is rare, THC can interact with other drugs and has a complex pharmacokinetic profile. THC is classified variably under international and US law, with medical use approved in multiple countries.

THC is short for tetrahydrocannabinol. It’s the main compound in cannabis, responsible for the intoxicating “high” you may feel when you consume some cannabis products.

THC, or tetrahydrocannabinol, is the primary psychoactive compound in cannabis, responsible for the plant’s euphoric effects. When consumed, THC interacts with receptors in the brain, altering neurotransmitter release and affecting mood, perception, and cognition.

What is THC? Discover its effects, medical uses, benefits, and potential risks. Everything you need to know about cannabis compounds.

THC, or delta-9-tetrahydrocannabinol, is the best-known psychoactive compound found in marijuana. Learn more about the effects, medicinal uses, and risks of THC.

Tetrahydrocannabinol, THC, is the active constituent of marijuana and hashish. It was first isolated from cannabis plants and synthesized in 1965.

The higher the THC amount, the stronger the effects on the brain—likely contributing to increased rates of marijuana-related emergency room visits. While there is no research yet on how higher potency affects the long-term risks of marijuana use, more THC is likely to lead to higher rates of dependency and addiction.

THC works by binding to specific sites in the brain and on the nerves. It's found in the highest levels in the leaves and flowers of the plant. THC is commonly used as a recreational drug.